Critical Care Medicine What is the 12 12 rule in mechanical ventilation? February 6, 2026 by Myaya | Leave a Comment The 12 12 rule in mechanical ventilation refers to a guideline often used in clinical settings to optimize the settings of a mechanical ventilator for a patient. This rule suggests setting the ventilator to deliver 12 breaths per minute with a tidal volume of 12 milliliters per kilogram of the patient’s ideal body weight. The […] Read more ยป