Home Science How hot to kill all germs? March 9, 2026 by Myaya | Leave a Comment To effectively kill all germs, you generally need to expose them to temperatures of at least 140°F (60°C) for a sustained period. This temperature is crucial for denaturing essential proteins and enzymes within microorganisms, rendering them inactive and preventing their reproduction. However, the exact temperature and duration required can vary depending on the specific type […] Read more »